MLB Games Today: Odds, Spreads & Picks

The full MLB slate for July 22, 2026: every game, the sharpest data-backed picks, and the angles worth knowing before you bet.

Quick Stats

• 25 games on the slate
• 20 qualifying trends tracked
• M. Dubon Over 0.5 - Runs Scored (100% in the last 10 hot games, +160) - ATL vs. SD
• Z. Littell Under 3.5 - Hits Allowed (100% in the last 20 games played on 0 days of rest, +425) - WSH vs. MIL
• S. Matz Under 3.5 - Hits Allowed (100% in the last 10 afternoon home games, +290) - TB vs. SF

Today's Slate

25 MLB games with odds and previews:

• Pittsburgh Pirates at New York Yankees
• Baltimore Orioles at Boston Red Sox
• New York Mets at Milwaukee Brewers
• San Francisco Giants at Kansas City Royals
• Washington Nationals at Colorado Rockies
• Las Vegas Athletics at Arizona Diamondbacks
• Cincinnati Reds at Seattle Mariners
• St. Louis Cardinals at Los Angeles Angels
• Minnesota Twins at Cleveland Guardians
• Los Angeles Dodgers at PHI Phillies
• Pittsburgh Pirates at New York Yankees
• Tampa Bay Rays at Toronto Blue Jays
• Baltimore Orioles at Boston Red Sox
• San Diego Padres at Atlanta Braves
• Chicago White Sox at Texas Rangers
• Miami Marlins at Houston Astros

Best Picks Across the Slate

Our highest-confidence plays today, with the data behind each:

• M. Dubon Over 0.5 - Runs Scored (100% in the last 10 hot games, +160) - ATL vs. SD
• Z. Littell Under 3.5 - Hits Allowed (100% in the last 20 games played on 0 days of rest, +425) - WSH vs. MIL
• S. Matz Under 3.5 - Hits Allowed (100% in the last 10 afternoon home games, +290) - TB vs. SF
• G. Jax Under 3.5 - Strikeouts Recorded (100% in the last 20 away games vs a former teammate, +225) - TB @ TOR
• J. Wrobleski Under 3.5 - Hits Allowed (100% in the last 5 cloudy away games, +330) - LAD @ STL

Things to Watch Out For

Slate-wide risk flags:

• Pittsburgh Pirates Pittsburgh Over 5.5 - Team Runs Scored has hit just 53% recently, closer to a coin flip than an edge.
• Pittsburgh Pirates Pittsburgh -1.5 - Run Line sits at 52% lately, too thin to back with confidence.

How We Read the Slate

Across 25 games we surface 20 qualifying trends, but volume alone is not edge, so we weight recent hit rate and matchup context before recommending a side.

Frequently Asked Questions

How many MLB games are on today?

25 games are on the current MLB slate.

What is the best MLB pick today?

Our top play: M. Dubon Over 0.5 - Runs Scored (100% in the last 10 hot games, +160) - ATL vs. SD.

Where can I see MLB odds?

Live odds and trends for every game appear in the widget feed on this page.